Products 2018-01-31T01:07:45+00:00

GenTegra-RNA protects RNA better

Shipping purified RNA can be safe and inexpensive using GenTegra-RNA.

GenTegra-RNA is quite simply the best protection available for your RNA. It is a water soluble Active Chemical Protection that when added to purified RNA allows it to be air-dried to form a protective matrix that preserves RNA in the dry state. The protection is near perfect at the extremes of temperature (-80°C to +56°C) for >4yrs. The protection is unmatched when it comes to protecting against the high temperatures encountered when shipping RNA samples. Independent studies show GenTegra-RNA protects better than shipping on dry ice. GenTegra-RNA is the only dry storage product that provides immediate protection against RNase activity before drying and allows the use of all standard buffer systems. Studies prove conclusively that GenTegra-RNA begins protecting your RNA the instant it is added to the RNA solution and protects RNA long-term better than storage at -20°C or -80°C and you save valuable freezer space. GenTegra-RNA is protected by an awarded US Patent.

All GenTegra-RNA products have a shelf life of 3-years at ambient temperatures

For ordering information click here.

The most convenient product format for the small laboratory is the 100, 0.5 ml screw cap tube package. GTR5100-S which is delivered in four sealed envelopes of 25 tubes each. This format is perfect for shipping samples between laboratories and for storing small numbers of RNA samples for later use.

Large usage of GenTegra-RNA means automation and product formats that support the automation requirements. This means ten packs of GenTegra microplates GTR4010-P or ten packs of 2D 96-tube racks GTR1010-BC. Both these formats lend well to the automation of purification and adding GenTegra-RNA, 96 samples at a time. If you are considering the use of GenTegra-RNA in an existing automated protocol, contact use for assistance in making the addition of GenTegra-RNA both quick and simple. Significant price reductions are available for large volume users of GenTegra-RNA.

For ordering information click here.

GenTegra-RNA is a water soluble chemical matrix that when combined with purified RNA allows it to be air-dried to form a solid matrix which preserves RNA in the dry state better than freezing. The GenTegra protection is near perfect at the extremes of temperature (-80°C to +56°C) for many years. This protection is unmatched when it comes to protecting against the high temperatures likely to be encountered when shipping samples. GenTegra-RNA is the only dry storage product that provides immediate protection against RNase activity and protects in all standard buffer systems. Studies prove conclusively that GenTegra-RNA begins protecting your RNA the instant it is added to the RNA solution and protects RNA long term better than storage at -20°C or -80°C and you save valuable freezer space. Accelerated temperature time studies show protection equivalent to >20 years. GenTegra-RNA has been protecting RNA since 2010 and is protected by an awarded US Patent.

Independent studies now show that using GenTegra-RNA to protect the RNA sample during shipping protects the RNA better than shipping on dry ice. The instant GenTegra-RNA is added to the purified RNA solution it begins to protect the RNA even in liquid form. With GenTegra-RNA added the solution may be used at room temperature for up to 48 hours without fear of RNA degradation. After the 48 hours the samples is dried and is now ready for long term storage or for shipping. When using GenTegra-RNA to ship samples between laboratories the savings in shipping costs will more than pay the costs of the GenTegra-RNA.

All GenTegra-RNA products have a shelf life of greater than 3-years at ambient temperatures.

The most convenient product format for the small laboratory is the 100, 0.5 ml screw cap tube package, GTR5100-S, which is delivered in four sealed envelopes of 25 tubes each. This format is perfect for shipping samples between laboratories and for storing small numbers of RNA samples for later use.

When the number of samples begins to reach a level where automation might be being considered then GenTegra-RNA in a 96-well microplate or a 96-tube rack may be a better fit to need. GTR4001-P and GTR1001 are both formats that match the standard 96 well microplate design and make handling larger numbers of samples easier. At this point it may also be reasonable to consider using the GTR100-B which is our bulk format that makes enough solution to add to 100 samples of RNA in any tube format you may be using.

If you would like to evaluate GenTegra-RNA in your laboratory, simply request a three tube evaluation kit GTR5003-S and we are happy to provide it at no charge. We do ask you to pay the shipping costs.

For ordering information click here.

GenTegra-DNA safely stores purified DNA at room temperature

GenTegra-DNA is a water soluble chemical matrix that when added to purified DNA allows it to be air-dried to form a solid matrix which coats, preserves and protects DNA in the dry state at ambient temperatures. The protection is near perfect at the extremes of temperature (-80°C to +56°C) for many years. GenTegra-DNA is especially valuable and effective at protecting against the high temperatures likely to be encountered when shipping samples. Studies prove conclusively that GenTegra-DNA protects DNA better than storage at -20°C or -80°C and you save valuable freezer space. GenTegra-DNA has been protecting DNA samples since 2009 and is protected by an awarded US Patent. All GenTegra-DNA products have an expected shelf life of greater than 3-years at ambient temperatures. Accelerated temperature time studies show protection equivalent to >20 years. GenTegra-DNA has been protecting DNA since 2008 and is protected by an awarded US Patent. No need for a desiccant, ice or dry ice when shipping. And because of the stability at ambient temperatures it simply does not matter if the sample is delayed in shipment, it will still arrive perfectly intact and ready to use.

Once the purified DNA has been combined with the GenTegra-DNA matrix and dried it is stable and protected. And once dried it stays dry because it is not hydroscopic and will not take up water. Long term archiving of the DNA sample does not require either humidity control or desiccant to keep the DNA safe.

All GenTegra-DNA products have a shelf life of 3-years at ambient temperatures.

For ordering information click here.

The most convenient product format for the small laboratory is the 100, 0.5 ml screw cap tube package. GTD2100-S which is delivered in four sealed envelopes of 25 tubes each. This format is perfect for shipping samples between laboratories and for storing small numbers of DNA samples for later use.

When the number of samples begins to reach a level where automation might be being considered then GenTegra-DNA in a 96-well microplate or a 96-tube rack may be a better fit to need. GTD4001-P and GTD1001 are both formats that match the standard 96 well microplate design and make handling larger numbers of samples easier. At this point it may also be reasonable to consider using the GTD100-B which is our bulk format that makes enough solution to add to 100 samples of DNA in any tube format you may be using.

If you would like to evaluate GenTegra-DNA in your laboratory, simply request a three-tube evaluation kit GTD2003-S and we are happy to provide it at no charge. We do ask you to pay the shipping costs.

For ordering information click here.

Large usage of GenTegra means automation and product formats that support the automation requirements. This means ten packs of GenTegra microplates GTD4010-P or ten packs of 2D 96-tube racks GTD1010-BC. Both these formats lend well to the automation of purification and adding GenTegra-DNA, 96 samples at a time. Laboratories that are automated may also want to simply add the GenTegra-DNA directly as part of their existing automation. This is support by our large volume bulk products that makes solutions ready to treat 2000 or 4000 samples a week both easy and economical.

Biobanking has begun to stabilize on the use of 2D barcode tubes to provide absolutely positive identification of each and every samples. GenTegra-DNA can be provided in the 2D barcode tube format with each tube already containing GenTegra-DNA or we can supply the GenTegra-DNA in the large bulk format and the automation system adds the GenTegra-DNA to the 2D barcoded tubes at the appropriate step in the automate process.

If you are considering the use of GenTegra-DNA in an existing automated protocol, contact use for assistance in making the addition of GenTegra-DNA both quick and simple. Pricing is such the GenTegra-DNA when used by a biobank to replace freezer storage the long-term cost saving are significant and ambient storage reduces storage space requirements for 30% to 300% depending upon the operation of the biobank. GenTegra offers a free consultation for any biobank or large use laboratory that wishes to investigate the cost and space saving of using GenTegra-DNA for the long term protect of their purified DNA samples.

For additional information please download the GenTegra-DNA User Guide on the Library page.

Collection cards for blood spots and biologicals

Collection cards are ideal for field sample collection in areas where a cold chain is unavailable or difficult to maintain. GenTegra offers cards for every need, DNA collection, RNA collection or sample collection for analysis of small molecule metabolites.

Ahlstrom-Munksjö GenSaver Card is the first new technology for collection and long-term storage of DNA in DBS in more than 20 years. GenSaver cards use the highly regarded and proven GenTegra®-DNA Active Chemical Protection™ on superior Ahlstrom paper. When collecting DBS for ambient temperature transportation or long-term DNA storage, this is the card of choice. It provides high levels of protection for the DNA during shipment and storage even at elevated temperatures. DBS on GenSaver cards can be used directly for PCR with no cleanup step required. A small punch can be added directly to the PCR mix without worrying about inhibition of the PCR reaction.

All Ahlstrom-Munksjö specimen collection cards are manufactured to ISO 18385 compliance, ensuring no human DNA contamination, so they are suitable for all forensic specimen collection needs as well as research specimen collection. Collection cards are available in all the common formats to meet your needs. The GenSaver cards are available I 1-spot, 2-spot & 4-spot formats and in color versions for use with clear samples. GenSaver cards also come in a 2.0 version designed for use in forensic applications where the samples may be dirty and need extra protection against microbial contamination.

For ordering information click here.

GenTegra GenProtect RNA is the first paper card designed to capture and protect RNA. Using the same Active Chemical Protection that protects purified RNA, GenTegra-RNA, has been re-formulated for a paper matrix allowing the easy field collection and protection of RNA in blood and other biological fluids. Once the blood spot is dried, the RNA is protected at ambient temperatures for up to 1-week. Protection includes the strong RNase inhibitor used in our highly regarded GenTegra-RNA. This new technology is currently in field testing phase. If you are interested in evaluating GenTegra GenProtect RNA cards, please contact GenTegra at orders@gentegra.com concerning availability. Quantities are available for testing.

For ordering information click here.

The Ahlstrom-Munksjö GenCollect card is a plain paper card without added chemicals and is designed for collection of samples that will be analyzed using MassSpec. This is the card of choice for collecting neonatal blood samples or for any sample that is to be used for small molecule analysis. The GenCollect card may also be used for DNA collection if the sample will be extracted and processed in a short period of time after collection. The GenCollect card is available in 1-spot, 2-spot & 3-spot formats and in a color version for clear samples such as saliva.

For ordering information click here.

Extract & Purify dsDNA from Dried Blood Spots

GenSolve DNA COMPLETE extracts and purifies more and better dsDNA from DBS on paper.

The GenSolve DNA COMPLETE kit combines the acknowledged superior quality and quantity of DNA extracted by GenSolve with an equally superior column based purification to yield the best and most DNA possible form Dried Blood Spots on paper. The combination is specifically designed to provide the very best results when working with DBS as the sample origin. Highest quality dsDNA can be efficiently recovered at higher yield from treated paper, i.e. GenSaver or FTA, and plain paper, i.e. GenCollect and Guthrie cards than using other techniques. The GenSolve reagents coupled with recovery process enhances digestion of dried biological material and liberates more bound DNA from the paper. The resulting lysate, which is a mixture of DNA, cellular debris and preservation chemicals, if applicable, is then applied directly onto a purification membrane. Subsequent washing steps separate the DNA from cellular material and a final elution step results in purified DNA ready for any genetic analysis techniques or for long term storage using GenTegra-DNA.

Once the purified DNA has been combined with the GenTegra-DNA matrix and dried it is stable and protected. And once dried it stays dry because it is not hydroscopic and will not take up water. Long term archiving of the DNA sample does not require either humidity control or desiccant to keep the DNA safe.

Additionally, you have the convenience of getting everything you need from one vendor.

For ordering information click here.

The GenSolve kit recovers double stranded DNA from paper spotted with blood or other biological liquids, regardless of storage time, for subsequent purification. DNA can be efficiently recovered at higher yield from treated paper, i.e. FTA, and untreated paper, i.e. Guthrie cards than using other techniques.

The GenSolve reagents coupled with recovery process enhances digestion of dried biological material and liberates more bound DNA from the paper. The resulting lysate, which is a mixture of DNA, cellular debris and FTA chemicals, if applicable, is then applied directly to your purification kit of choice. Using the GenSolve chemistry will yield highest levels of DNA no matter what your choice of purification kit.

For ordering information click here.

GenPlates® Safely store blood, buffy coat & plasma at room temperature

GenPlates are an automation friendly 398 well format for storing raw blood, buffy coat, saliva and other fluid biospecimens at room temperature for later extraction of high quality dsDNA.

GenPlates®: are an automation friendly, high density format for biobanking of blood and other biological fluids on FTA paper. The GenPlate is a high density 384-microplate format with a 6-mm disc of FTA paper in each well. FTA paper has been, for decades now, the de-facto standard for protecting DNA that is stored on paper as dried blood spots. GenPlates have been storing and protecting DNA in dried blood spots since 2006, and are protected by US and Int. Patents. GenPlates are available in several formats to best fits the storage needs of your samples.

For ordering information click here.

Our most popular GenPlate format is the 24 region GenPlate that stores blood spots from 24 subjects and each subject has 4 replicates stored on the GenPlate. All current sequencing technologies can now do deep whole genome sequencing on the DNA extracted from on 6 mm disc. And all the extra DNA is often put onto GenTegra-DNA to preserve it for later use as need. The four replicates ensure that another sample is always available when needed.

Dried blood spots on FTA paper require storage in a humidity controlled environment to ensure the samples are properly protected from future contamination. GenTegra also supplies cabinets and archives that provide active humidity control for the storage of GenPlates. Each GenPlate has a unique barcode on it and the Personal Archive offers a storage cabinet that provides a unique 2D barcode for each and every storage location within the archive.

For additional information please download the GenPlate User Guide from the Library page.

Archives to Safely & Efficiently store samples

GenTegra Archives hold a wide variety of standard laboratory storage media and offer convenience, organization and low-cost sample storage

The GenStore Archive is a high capacity moderate cost storage cabinet that can be tailored to the storage needs of the laboratory. Design primarily for the storage of GenTegra-DNA and GenTegra-RNA protected samples the GenStore cabinet does not require humidity control and has a capacity for 460,800 discrete samples in standard 96-well microplate format.

When storing GenPlates the GenStore Archive requires the optional active dehumidifier to keep the GenPlate samples dry and stable. The GenStore Archive has the capacity to store 8,880 GenPlates.

For ordering information click here.

The Personal Archive is an efficient high-density method for storing hundreds of thousands of biosamples dried on GenPlates. In about 9.5 square feet of floor space over 2,400 GenPlates can be easily stored and just as easily retrieved. Depending upon the configuration of the GenPlate used as many as 172,800 discrete sample aliquots can be archived. The personal archive is well suited for organizations that collect a relatively large number of dried blood spot samples for their personal research efforts. Each Personal archive comes equip with a 2D barcode hand scanner and an active dehumidifier to keep the GenPlates dry and stable. Each drawer of the Personal archive locks to keep samples secure.

For ordering information click here.

FastDryer™ makes drying samples easy

This FastDryer (GVGT2001) is a simple, economical and convenient way to dry biosamples following application to GenTegra-DNA or GenTegra-RNA. Each FastDryer will accept one 96-well microplates, one rack of 0.3 ml cluster tubes, one GenPlate or up to 48, 0.5 ml, screw-cap tubes. Most samples of ≤ 50 µl will be dried overnight and be ready for storage in the morning. The FastDryer has been tested and shows no carryover between samples.

For ordering information click here.

This FastDryer (GVGT-6000) is a larger version that can hold up to six standard microplates, cluster tube racks or GenPlates. It also holds up to 144, o.5 ml, screw cap tubes. Most samples of ≤ 50 µl will be dried overnight and be ready for storage in the morning. The FastDryer has been tested and shows no carryover between samples.

For ordering information click here.

Implementing Ambient Biobanking

Biobanks are lean organizations with little if any spare time and any change being considered must be done in a way that minimizes its impact on the day to day operation. Our consultation service is designed to identify the best way to implement dry ambient storage technology into the biobank’s operation while ensuring a minimum impact on process, personnel and expenses. The consultation service is free of charge and is provided according to the biobank’s schedule.

Consultation starts with a three-page questionnaire answered in writing or through a one-on one conversation to understand the present operations and processes of the biobank/biorepository.
If the initial questionnaire was in writing a follow-up conversation or teleconference is arranged to further discuss and understand the detailed operation 0f the lab.

A written report is then prepared by GenTegra summarizing the biobanks operation and reviewed by the biobank staff. Once the report is approved, with or without edits a final report issued.

With the final report approved a proposal is generated outlining effective and efficient methods for beginning the implementation and adoption of ambient temperature storage and the use of Active chemical technology in the biobank. Key areas of concern in the proposal are minimizing the impact on the biobank as the new Active chemical technology is adopted. The concerns are to minimize impacts to the operations and to minimize the costs of adopting Active chemical technology.

Contact GenTegra at info@gentegra.com if you are interested in a consultation.

To begin the process please use the questionnaire here.

OEM products and Custom formulations

GenTegra is ready to provide private label versions of our protective technologies to companies that need a better and cheaper alternative to shipping temperature sensitive samples on dry ice or wet ice.

If shipping samples or products on dry ice is causing you both high costs and lost samples due to shipping delays GenTegra may be able to help. We are available to provide our technology, such as GenTegra-RNA in either a private label OEM or our GenTegra-INSIDE co-branding products.

Contact us at info@gentegra.com and we will happily work with you to solve your stability issues.

GenTegra has technologies for stabilizing biological molecules other than nucleic acids and is ready to discuss how we might provide you with a solution to any instability problem you might have.

Contact GenTegra at info@gentegra.com and we will happily work with you to solve your stability issues.